BRUKINSA (zanubrutinib) Logo
BRUKINSA (zanubrutinib) Logo

BRUKINSA patients can call the myBeiGene® patient support program to talk to a dedicated nurse: 1-833-BEIGENE (1-833-234-4363)

Dosing options that help you take control

BRUKINSA is the only BTK inhibitor that offers the choice of 2 dosing schedules

Your doctor can prescribe BRUKINSA either once daily or twice daily

BRUKINSA is an oral prescription medicine with a recommended dose of 320 mg daily taken as four 80-mg capsules, with or without food.

Talk to your doctor about which dosing schedule is best for you

Take BRUKINSA exactly as prescribed
  • Do not switch your dosing schedule without discussing with your doctor first
  • BRUKINSA capsules should be taken whole with water—do not open, break, or chew
If you miss a dose of BRUKINSA, take it as soon as you remember

Try and take it on the same day. Return to your normal schedule the next day.

Tell your doctor about all the medications you are currently taking

This includes prescription and over-the-counter medicines, vitamins, and herbal supplements.

Want to learn more about your treatment with BRUKINSA?can help

To meet your individual needs, myBeiGene pairs you with a dedicated Oncology Nurse Advocate who will personalize support for you and your caregivers during your treatment with BRUKINSA.

Call 1-833-BEIGENE (1-833-234-4363) Monday through Friday, 8 AM to 8 PM Eastern Time to speak with an Oncology Nurse Advocate today.

VISIT myBeiGene.com TO LEARN MORE

myBeiGene® is not insurance and does not guarantee product coverage or reimbursement.

IMPORTANT SAFETY INFORMATION

What should I tell my healthcare provider before taking BRUKINSA?

Before taking BRUKINSA, tell your healthcare provider about all of your medical conditions, including if you:

  • have bleeding problems.
  • have had recent surgery or plan to have surgery. Your healthcare provider may stop BRUKINSA for any planned medical, surgical, or dental procedure.
  • have an infection.
  • have or had heart rhythm problems.
  • have high blood pressure.
  • have liver problems, including a history of hepatitis B virus (HBV) infection.
  • are pregnant or plan to become pregnant. BRUKINSA can harm your unborn baby. If you are able to become pregnant, your healthcare provider may do a pregnancy test before starting treatment with BRUKINSA.
    • Females should avoid getting pregnant during treatment and for 1 week after the last dose of BRUKINSA. You should use effective birth control (contraception) during treatment and for 1 week after the last dose of BRUKINSA.
    • Males should avoid getting female partners pregnant during treatment and for 1 week after the last dose of BRUKINSA. You should use effective birth control (contraception) during treatment and for 1 week after the last dose of BRUKINSA.
  • are breastfeeding or plan to breastfeed. It is not known if BRUKINSA passes into your breast milk. Do not breastfeed during treatment with BRUKINSA and for 2 weeks after the last dose of BRUKINSA.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking BRUKINSA with certain other medications may affect how BRUKINSA works and can cause side effects.

What are the possible side effects of BRUKINSA?

BRUKINSA may cause serious side effects, including:

  • Bleeding problems (hemorrhage). Bleeding problems are common with BRUKINSA, and can be serious and may lead to death. Your risk of bleeding may increase if you are also taking a blood thinner medicine. Tell your healthcare provider if you have any signs or symptoms of bleeding, including:
    • blood in your stools or black stools (looks like tar)
    • pink or brown urine
    • unexpected bleeding, or bleeding that is severe or you cannot control
    • vomit blood or vomit that looks like coffee grounds
    • cough up blood or blood clots
    • increased bruising
    • dizziness
    • weakness
    • confusion
    • change in speech
    • headache that lasts a long time
  • Infections that can be serious and may lead to death. Tell your healthcare provider right away if you have fever, chills, or flu-like symptoms.
  • Decrease in blood cell counts (white blood cells, platelets, and red blood cells). Your healthcare provider should do blood tests during treatment with BRUKINSA to check your blood counts.
  • Second primary cancers. New cancers have happened in people during treatment with BRUKINSA, including cancers of the skin or other organs. Your healthcare provider will check you for other cancers during treatment with BRUKINSA. Use sun protection when you are outside in sunlight.
  • Heart rhythm problems (atrial fibrillation, atrial flutter, and ventricular arrhythmias) that can be serious and may lead to death. Tell your healthcare provider if you have any of the following signs or symptoms:
    • your heartbeat is fast or irregular
    • feel lightheaded or dizzy
    • pass out (faint)
    • shortness of breath
    • chest discomfort

The most common side effects of BRUKINSA include:

  • decreased white blood cell count
  • upper respiratory tract infection
  • decreased platelet count
  • muscle, bone, or joint pain

These are not all the possible side effects of BRUKINSA. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is BRUKINSA?

BRUKINSA is a prescription medicine used to treat adults with:

  • Chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
  • Waldenström’s macroglobulinemia (WM).
  • Mantle cell lymphoma (MCL) who have received at least one prior treatment for their cancer.
  • Marginal zone lymphoma (MZL) when the disease has come back or did not respond to treatment and who have received at least one certain type of treatment.

It is not known if BRUKINSA is safe and effective in children.

Please see full Prescribing Information including Patient Information.

Learn more about treatment with BRUKINSA

CLL/SLLWMMCL
BRUKINSA for MZL
BeiGene, Ltd. Opens in a new window.
Privacy Policy